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Functional enrichment methods and pathways

For some time I have been working on one topic. I am not sure if this is how it started but I fail to see other reasons. So I'll describe why I'm now working with gene sets collections. The trigger I usually try to help others in Biostars , Bioconductor , and in the StackExchange network (specially in Bioinformatics ). On one of these sites I was trying to help some person, and in one of the comments ( Jun 21 '17 ) it says: You don't build pathway maps from bioinformatics data, you build them from wet-lab experiments. And I was : " Why not? We already know (kind of) the number of genes, and we have an idea or the number of metabolites in a cell. We have many data, why can't we build pathways?" But I did a brief literature search and I couldn't find anything (if there is something let me know in the comments).   The background Let me explain why this comment got me puzzled: in my work I am usually asked what is the relevan...

Bioconductor histories with git-svn

If you are developing a software you might be using a version control (If not do it :). Bioconductor until 05/2017 is using svn. However it is migrating to git, meanwhile a hybrid system is provided, where one submits the project through GitHub using git control version system and internally it uses svn. Here are some experiences developing in for Bioconductor in this configuration . After following the recommendations of the configuration .git/config ends up with: [core]     repositoryformatversion = 0     filemode = true     bare = false     logallrefupdates = true [remote "origin"]     url = https://github.com/llrs/BioCor.git     fetch = +refs/heads/*:refs/remotes/origin/* [branch "master"]     remote = origin     merge = refs/heads/master [remote "bioc"]     url = https://github.com/Bioconductor-mirror/BioCor.git     ...

BioCor: My first package in Bioconductor

Yesterday I received an amazing email: Congratulations, BioCor has been added to Bioconductor! Yes, I had submitted a package for the Bioconductor project at the beginning of the week. The package calculates similarities between pathways, genes and clusters of genes based on their pathways. A pathway is a group of functionally related proteins, thus this similarities calculates the functional similarity of the pathway or genes in question. If anyone is curious what the email had this was in the body (I didn't know what to expect when I knew that it would be accepted):  Hi Lluís, Congratulations, BioCor has been added to Bioconductor! Currently, the definitive location for your Bioconductor package is in our SVN repository. The following information is to help you in your role as a package maintainer. You’ll need the following credentials to maintain your package: Subversion user ID: myuser Password: mypassword Package ‘landing pages’ Every package in Bi...